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Key role for ubiquitin protein modification in TGFβ signal transduction

✍ Scribed by De Boeck, Miriam; Ten Dijke, Peter

Book ID
125422574
Publisher
Informa plc
Year
2012
Tongue
English
Weight
399 KB
Volume
117
Category
Article
ISSN
0300-9734

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## Abstract TGF‐β1 induces cell cycle activation in mouse embryonic fibroblasts by down regulation of p27^Kip1^ but it can also induce delay of EGF‐induced cell cycle activation in these cells under similar conditions. In an attempt to determine the basis for these responses, the study of early TGF