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Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers

✍ Scribed by W. Ridtitid; M. Wongnawa; W. Mahatthanatrakul; N. Raungsri; M. Sunbhanich

Book ID
108848867
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
110 KB
Volume
30
Category
Article
ISSN
0269-4727

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Whole blood concentrations of mefloquine
Whole blood concentrations of mefloquine enantiomers in healthy Thai volunteers
✍ C. Martin; F. Gimenez; K. N. Bangchang; J. Karbwang; R. Farinotti; I. W. Wainer πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 251 KB

We studied the pharmacokinetics of the enantiomers of mefloquine in whole blood in healthy Thai volunteers after administration of a single oral dose of 750 mg of the racemic mixture. Mefloquine pharmacokinetics were stereoselective. The peak concentrations and areas under the curve of the (-) enant