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Ketene-S,S-acetals-V : The reactions of α-keto and α-cyanoketene-S,S-acetals with guanidine and thiourea: a new general synthesis of alkoxy-pyrimidines

✍ Scribed by S.M.S. Chauhan; H. Junjappa


Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
1015 KB
Volume
32
Category
Article
ISSN
0040-4020

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A new catalytic C À C bond-forming reaction has been developed. Catalyzed by cheap and commercially available copper(II) bromide (CuBr 2 ; 10 mol%), the reactions of a-electron-withdrawing group (EWG)-substituted ketene S,S-acetals with aldehydes or ketones in acetonitrile at room temperature gave a