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Ketanserin and tetrabenazine abolish aggression in mice lacking monoamine oxidase A

✍ Scribed by Jean Chen Shih; Michael James Ridd; Kevin Chen; Woerner Pauls Meehan; Mei-Ping Kung; Isabelle Seif; Edward De Maeyer

Book ID
114004985
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
526 KB
Volume
835
Category
Article
ISSN
0006-8993

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## Abstract The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rate‐limiting enzyme in serotonin (5‐HT) biosynthesis, and on the levels of 5‐HT and 5‐hydroxyindoleacetic acid (5‐HIAA) in the midbrain, hyp