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Ketamine and the next generation of antidepressants with a rapid onset of action

✍ Scribed by Rodrigo Machado-Vieira; Giacomo Salvadore; Nancy DiazGranados; Carlos A. Zarate Jr.

Book ID
113845946
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
386 KB
Volume
123
Category
Article
ISSN
0163-7258

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Existing antidepressant treatments suffer from a limited efficacy and a slow onset of action. Some first-generation antidepressant drugs are still among the most effective treatments. Several neurobiological adaptive mechanisms are involved in the delayed action of antidepressants. Among these, a ne