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Keratinocyte growth factor (KGF) is required for post-natal thymic regeneration

✍ Scribed by O. Alpdogan; V.M. Hubbard; S.J. Muriglan; G.L. Goldberg; A.A. Kochman; J.M. Eng; O.M. Smith; R.L. Boyd; M.R.M. van den Brink


Book ID
116278126
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
54 KB
Volume
11
Category
Article
ISSN
1083-8791

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Transforming growth factor ␀ (TGF-␀) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-␀ signaling in liver regeneration in vivo, the TGF-␀ type II receptor gene (Tgfbr2) was selectively del