Keratin 19 mRNA is detectable by RT-PCR in lymph nodes of patients without breast cancer
โ Scribed by Yun, K; Gunn, J; Merrie, AEH; Phillips, LV; McCall, JL
- Book ID
- 109837447
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 153 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0007-0920
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๐ SIMILAR VOLUMES
This study was undertaken to assess a multiple-marker RT-PCR and Southern blot assay for detection of metastases in frozen sections of sentinel lymph nodes from breast cancer patients. Sentinel lymphadenectomy was performed in 41 AJCC (American Joint Committee on Cancer) stage I-IIIA breast cancer p
BACKGROUND. Amplification of keratin 19 mRNA (K19) by reverse transcriptasepolymerase chain reaction (RT-PCR) has been shown to be a sensitive method to detect occult breast cancer metastases in lymph nodes. METHODS. Axillary lymph nodes were obtained from 126 patients with breast cancer, and metast