Pilot studies were conducted to evaluate the toxicity and efficacy of two relatively marrow-sparing chemotherapy regimens in the treatment of advanced or progressive epidemic Kaposi's sarcoma. Chemotherapy regimens consisted of bleomycin (10 mg/m2), vincristine (1.4 mg/m2, 2 mg maximum) and Adriamyc
Kaposi's sarcoma in the acquired immune deficiency syndrome
β Scribed by Leslie, William ;Templeton, Alex ;Braun, Donald
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 775 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0098-1532
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β¦ Synopsis
I]. This is still a good description of the lesions seen in Kaposi's sarcoma. Usually the lesions are multicentric and may coalesce to form large plaques or tumors which can ulcerate. Spontaneous regression is occasionally seen. Invasion of deep soft tissues or bone and visceral involvement was seen most frequently, prior to 1980, in the African form of the disease.
The average duration of survival in the classic form of Kaposi's sarcoma is 8 to 13 years. Older patients often die of other diseases during that time. Until recently, the reported annual incidence of Kaposi's sarcoma in North America and Europe was 0.02 to 0.06 per 100,000 [2]. It was most common in men over 50 years of age, and From the Section of Medical Oncology, Department of Medicine (W.L., D.B.) and Department of' Pathology (A.T.), Rush-Presbyterian-St. Luke's Medical Center, Chicago.
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