Background: Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. ## Results: We have identified target genes of Wnt signaling using microarray technology and human embryonic
โฆ LIBER โฆ
K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin
โ Scribed by RUTHERFORD, T. R.; CLEGG, J. B.; WEATHERALL, D. J.
- Book ID
- 109714520
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 250 KB
- Volume
- 280
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/280164a0
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## Abstract Fas and FasL expression upregulation was found in human leukemia K562 cells upon exposure to __Naja naja atra__ phospholipase A~2~ (PLA~2~). PLA~2~ treatment induced an increase in intracellular Ca^2+^ ([Ca^2+^]i) and ROS generation levels, leading to activation of p38 MAPK and JNK. Sup