K562 cells express human major histocompatibility antigens
✍ Scribed by Andreas Ziegler; Dietmar Laudien; Hubert Heinrichs; Claudia Müller; Barbara Uchańska-Ziegler; Peter Wernet
- Publisher
- Springer-Verlag
- Year
- 1981
- Tongue
- English
- Weight
- 467 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0093-7711
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Rat insulinoma cells clone 5AH-B, were transfected by electroporation with the gene encoding the mouse major histocompatibility complex class I antigen H-2Kb, whereupon stable transfectants were selected and analysed. Data from flow cytometric analyses using three different H-2Kb specific monoclonal
## Modulation of expression of class I1 histocompatibility antigens by secretion of a cellular inhibitor in K562 leukemic cells In this report we show that it is possible to induce the expression of HLA-DR antigens on K562 cells, previously reported to be unresponsive to interferon-gamma (IFN-y).