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K40E: a novel succinate dehydrogenase (SDH)B mutation causing familial phaeochromocytoma and paraganglioma

✍ Scribed by Ciara M. McDonnell; Diana E. Benn; Deborah J. Marsh; Bruce G. Robinson; Margaret R. Zacharin


Book ID
118700222
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
157 KB
Volume
61
Category
Article
ISSN
0300-0664

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## Abstract ## Background Paragangliomas of the head and neck are rare, mostly benign tumors. Approximately 10% to 15% of paragangliomas are caused by mutations in the succinate dehydrogenase (SDH) genes B, C, or D. These are often multifocal as part of paraganglioma syndromes and hormone secretin