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K-ras pathways regulate VEGF in hypoxia independent of HIF-1 in colon cancer

✍ Scribed by Yusuke Mizukami; Jingnan Li; Xiaobo Zhang; Daniel C. Chung

Book ID
119427027
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
172 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract We examined how ionizing radiation (IR) delivered under either severe hypoxia (< 0.1% O~2~) or normoxia affects the expression of hypoxia inducible factor 1Ξ± (HIF‐1Ξ±) and the angiogenic factors vascular endothelial growth factor (VEGF) and angiopoietins 1, 2 and 4 in U87 human glioblast