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K-ras mutations in klatskin-tumors and in klatskin-mimicking lesions

✍ Scribed by JR Izbicki; KL Prenzel; A Niendorf; WT Knoefel; A Gebhardt; SB Hosch; B Passlick; D Evans; X Rogiers; CE Broelsch

Book ID: 118879950
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 151 KB
Volume: 108
Category: Article
ISSN: 0016-5085
DOI: 10.1016/0016-5085(95)26255-5

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## Abstract __K‐ras__ and mucin profile variations, associated with intestinal carcinogenesis, were studied in the preneoplastic lesions, mucin‐depleted foci (MDF) and aberrant crypt foci (ACF), and in colonic tumors induced in rats by 1,2‐dimethylhydrazine (DMH). The frequency of lesions with __K‐