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K-ras mutations in colorectal adenocarcinomas and neighbouring transitional mucosa

✍ Scribed by H Zhang; B Nordenskjöld; M Dufmats; P Söderkvist; X.-F Sun


Book ID
117665984
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
93 KB
Volume
34
Category
Article
ISSN
0959-8049

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Ki-ras MUTATIONS IN ADENOMAS: A CHARACTE
✍ MORRIS, ROBERT G.; CURTIS, LUCY J.; ROMANOWSKI, PIOTR; HARDCASTLE, JACK D.; JENK 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 652 KB

Activating mutations in the Ki-ras2 oncogene are frequently observed in sporadic colorectal adenomas and their incidence is reported to rise in large and tubulovillous adenomas to values close to those in carcinomas. This study shows that this property is a feature of adenomas growing in large bowel