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K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location

✍ Scribed by Breivik, J; Meling, GI; Spurkland, A; Rognum, TO; Gaudernack, G


Book ID
109837076
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
865 KB
Volume
69
Category
Article
ISSN
0007-0920

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## Abstract Material from paraffin sections of 109 human colorectal carcinomas, mostly obtained at autopsy, was analyzed for the presence of K‐__ras__ point mutations at codon 12, position 2. Mutations at this position were found in 23 cases (21.1%). Aneuploid colorectal carcinomas showed a signifi