✦ LIBER ✦
K-Opioid activity of the four stereoisomers of the peripherally selective κ-agonists, EMD 60 400 and emd 61 753
✍ Scribed by Dr. Rudolf Gottschlich; Michael Krug; Andrew Barber; Ralf M. Devant
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 372 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
✦ Synopsis
The four stereoisomers of the two peripherally selective K-opioid agonists EMD 60 400 and EMD 61 753 were synthesized, tested for stereoisomeric purity, and examined for affinity to the K opioid receptor. The relationships between the configuration of these molecules and their biological activity are discussed. o 1994 wiey-Liss, hc.