𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Juvenile parkinsonism: A patient with possible primary striatal dysfunction

✍ Scribed by Sakkubai Naidu; Dr Leslie I. Wolfson; Nansie S. Sharpless

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
310 KB
Volume
3
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A 15‐year‐old boy who initially manifested dystonic features and later developed classic parkinsonism is described. Cerebrospinal fluid homovanillic acid levels were normal or slightly elevated both before and after administration of probenecid. The patient responded favorably to treatment with levodopa and carbidopa. The normal or slightly elevated cerebrospinal fluid homovanillic acid levels contrast with the low levels usually seen in adult parkinsonian patients. The data on this patient suggest direct neostriatal involvement rather than depletion of neurons of the substantia nigra. Juvenile parkinsonism may have at least two distinct pathological forms, but they have similar clinical features and a similar response to treatment.

πŸ“œ SIMILAR VOLUMES

Primary pulmonary hypertension in a pati
Primary pulmonary hypertension in a patient with systemic-onset juvenile arthritis
✍ Shai Padeh; Ronald M. Laxer; Meredith M. Silver; Earl D. Silverman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 582 KB

We describe a 16-year-old girl with systemic-onset juvenile arthritis who presented with pulmonary hypertension, without evidence of pleural or parenchymal involvement of the lung, pulmonary vasculitis, or immune deposition in the pulmonary vasculature. Pleuropulmonary involvement occurs occasionall

A progressive, fatal dystonia-Parkinsoni
A progressive, fatal dystonia-Parkinsonism syndrome in a patient with primary immunodeficiency receiving chronic IVIG therapy
✍ Spiridon Papapetropoulos; Jennifer Friedman; Craig Blackstone; Gary I. Kleiner; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 76 KB

## Abstract X‐linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by a mutation in the Bruton agammaglobulinemia tyrosine kinase gene that results in severe B‐cell deficiency. So far, neurological complications of XLA have been primarily related to acute and/or chronic cen

Pathological gambling in patients with P
Pathological gambling in patients with Parkinson's disease is associated with fronto-striatal disconnection: A path modeling analysis
✍ Roberto Cilia; Sang Soo Cho; Thilo van Eimeren; Giorgio Marotta; Chiara Siri; Ji πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 374 KB

Background: Pathological gambling may occur in Parkinson's disease (PD) as a complication of dopaminergic therapy. Neuroimaging studies have suggested an abnormal dopamine transmission within the reward system, but the changes in the neural network characterizing PD patients with pathological gambli

Long-term changes of striatal dopamine D
Long-term changes of striatal dopamine D2 Receptors in patients with Parkinson's disease: A study with positron emission tomography and [11C]Raclopride
✍ Angelo Antonini; Johannes Schwarz; Wolfgang H. Oertel; Oliver Pogarell; Prof. Kl πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 574 KB

## Abstract We used [^11^C]raclopride (RACLO) and positron emission tomography (PET) to study longitudinally striatal dopamine D~2~ receptor binding in nine patients with Parkinson's disease (PD) at an early drug‐naive stage and 3–5 years later, when motor fluctuations had appeared in seven of them