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Juncenolides H – K, New Briarane Diterpenoids from Junceella juncea

✍ Scribed by Shih-Sheng Wang; Yu-Hui Chen; Jiun-Yang Chang; Tsong-Long Hwang; Chung-Hsiung Chen; Ashraf Taha Khalil; Ya-Ching Shen

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
210 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Chemical investigation of the Taiwanese gorgonian coral Junceella juncea resulted in the isolation of four new briarane‐type diterpenoids, juncenolides H, I, J, and K (1–4). Their structures were determined on the basis of spectroscopic analysis, especially 1‐ and 2D‐NMR. The inhibitory effects of compounds 1–4 on superoxide‐anion generation and elastase release by human neutrophils were evaluated.

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