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Journey through the thymus: stromal guides for T-cell development and selection

✍ Scribed by Takahama, Yousuke


Book ID
109955315
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
663 KB
Volume
6
Category
Article
ISSN
1474-1741

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GATA-3 is a zinc-finger transcription factor that is essential for both early T cell development and Th2 cell differentiation. To quantify GATA-3 expression during T cell development in vivo in the mouse, the GATA-3 gene was targeted by insertion of a lacZ reporter by homologous recombination in emb