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Joint One-Sided and Two-Sided Simultaneous Confidence Intervals

โœ Scribed by Braat, S.; Gerhard, D.; Hothorn, L. A.


Book ID
127054368
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
349 KB
Volume
18
Category
Article
ISSN
1054-3406

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One-sided Simultaneous Confidence Interv
โœ Ludwig A. Hothorn; Frank Bretz ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 108 KB ๐Ÿ‘ 1 views

An important issue in dose finding is whether a further dose increment leads to a relevant increase in efficacy. Clinical efficacy should not be considered by point zero null hypotheses. Instead, shifted hypotheses for the difference or the ratio can be used. Because the a priori definition of a rel