In a study involving 276 nurses in a large hospital in Northern Ireland, a comprehensive set of questionnaires was administered to assess multiple job-related variables. Nurses in general appeared to display high scores on the stresses related to con®dence and competency in role, home±work con¯ict, and organisational involvement (subscales which are themselves closely associated with demands in social interaction at work). These are stresses which were related to psychological well-being. There were no gender differences on occupational stress or the health outcome variables. Age did emerge as signi®cantly related to total stress and mental health (older nurses reporting more stress, and the younger nurses experiencing better psychological health). Grade of nursing was unrelated to job stress and outcome health variables, including work satisfaction. Although no differences were observed between wards/specialism and stress, differences were revealed along satisfaction, with maternity nurses (and intensive care nurses) displaying the highest level of satisfaction at work, and surgical (and medical) nurses showing the lowest. Finally, Type A emerged as a signi®cant determinant of physical health, in contrast to internal locus of control, which was more related to mental health, (lower) occupational stress, and job satisfaction. No signi®cant Type A Â locus of control interactions were observed. The implications of these ®ndings for nursing care are discussed.