JNK signaling in apoptosis
β Scribed by Dhanasekaran, D N; Reddy, E P
- Book ID
- 109970626
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 239 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0950-9232
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## Abstract The JNK signaling pathway is involved in regulation of many cellular events, including growth control, transformation and programmed cell death (apoptosis). The role of JNK activation in apoptosis is highly controversial, being suggested to have a proβapoptotic, antiβapoptotic or no rol
## Abstract Activation of the cβJun Nβterminal kinase (JNK) pathway is suggested to be required for neuronal apoptosis. We investigated the role of JNK on phosphorylation of cβJun, Bclβ2, and apoptotic translocation of cytochrome c (cyt c) in UVβinduced apoptosis in human neuroblastoma SHβSY5Y cell