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JH rearrangements in Hodgkin's disease

✍ Scribed by Nigel O'Connor


Book ID
119484535
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
95 KB
Volume
18
Category
Article
ISSN
1532-8392

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MOLECULAR ANALYSIS OF THENPM-ALK REARRAN
✍ XERRI, LUC; PARC, PATRICIA; HASSOUN, JACQUES; BIRNBAUM, DANIEL πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 566 KB

The fusion gene NPM-ALK occurs in a subset of anaplastic large cell lymphomas (ALCLs), as a result of a chromosomal translocation, t(2;5) (p23;q35). It has been suggested that Hodgkin's disease (HD) and ALCL share a common histogenesis because of pathological and phenotypical similarities. In order