Jasonol, a rare tricyclic eudesmane sesquiterpene and six other new sesquiterpenoids from Jasonia candicans

✍ Scribed by Ahmed A. Ahmed; Ahmed A. Mahmoud

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 629 KB
• Volume: 54
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(98)00453-0

✦ Synopsis

The extract of the leaves of,/asonia candicans yielded, seven new sesquiterpenes and sesquiterpene lactones including a eudesmane containing a rare type 0f6/6/4 membered ring system, two 7-epi-eudesmanes (12-hydroxyisointermedeol and 7-epi-ilicic acid), two guaianolides (inuviscolide and its 8-epi-derivative), iphionane and cadinane-triol derivatives. The structures were elucidated by spectroscopic analysis particularly high-resolution 1D and 2D NMR spectroscopy and the extensive NOE analysis.