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Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer

✍ Scribed by Sakamoto, K; Triplett, A A; Schuler, L A; Wagner, K-U


Book ID
109972455
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
922 KB
Volume
29
Category
Article
ISSN
0950-9232

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## Abstract The oncogenic transcription factor Stat3 is constitutively active in a high percentage of human tumors including mammary adenocarcinomas and is reported to participate in the ErbB‐2 oncogene signaling. In order to assess the role of signal transducer and activator of transcription 3 (St