𝔖 Bobbio Scriptorium
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James Neel and the doubling dose concept

✍ Scribed by Mary F. Lyon

Book ID
117768141
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
61 KB
Volume
543
Category
Article
ISSN
1383-5742

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The in vivo infusion of Bromodeoxyuridine (BrdUrd), followed by delayed biopsy and bivariate DNA-BrdUrd flow cytometry, allows the potential doubling time (T pot ) of human tumors to be estimated. According to Steel, the mathematical definition of T pot is T pot ‫؍‬ ln 2/K p , where K p is the rate