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IV007 A dominant role of Toll-like receptor 4 (TLR4) in the signaling of apoptosis in bacteria-faced macrophages


Book ID
117776907
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
65 KB
Volume
293
Category
Article
ISSN
1433-1128

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## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Toll‐like receptors (TLR). Although mitogen‐activated protein kinases (MAPK) are key ele