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Itraconazole Formulation Studies of the Melt-Extrusion Process with Mixture Design

โœ Scribed by Rambali, B.; Verreck, G.; Baert, L.; Massart, D. L.

Book ID
120710152
Publisher
Informa plc
Year
2003
Tongue
English
Weight
326 KB
Volume
29
Category
Article
ISSN
0363-9045

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Fusion processing of itraconazole solid
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โœ James C. DiNunzio; Chris Brough; Dave A. Miller; Robert O. Williams III; James W ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 287 KB

KinetiSol Dispersing (KSD) is a novel high energy manufacturing process investigated here for the production of pharmaceutical solid dispersions. Solid dispersions of itraconazole (ITZ) and hypromellose were produced by KSD and compared to identical formulations produced by hot melt extrusion (HME).