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iStable: off-the-shelf predictor integration for predicting protein stability changes

โœ Scribed by Chi-Wei Chen, Jerome Lin, Yen-Wei Chu


Book ID
120675340
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
703 KB
Volume
14
Category
Article
ISSN
1471-2105

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โœ Lauren Wickstrom; Emilio Gallicchio; Ronald M. Levy ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 559 KB

## Abstract The coupling of protein energetics and sequence changes is a critical aspect of computational protein design, as well as for the understanding of protein evolution, human disease, and drug resistance. To study the molecular basis for this coupling, computational tools must be sufficient