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Isozyme- and gender-specific induction of glutathioneS-transferases by flavonoids

โœ Scribed by Alyson E. Mitchell; Stephanie A. Burns; Jaime L. Rudolf

Book ID
105870569
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
397 KB
Volume
81
Category
Article
ISSN
0340-5761

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Glutathione S-transferases (GST, E.C.2.5.1.18) comprise a family of detoxification enzymes. Elevated levels of specific GST isozymes in tumor cells are thought responsible for resistance to chemotherapeutics, which renders selective GST inhibitors potentially useful pharmaceutical agents. We discuss