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Isovaline attenuates epileptiform activity and seizure behavior in 4-aminopyridine treated rats

✍ Scribed by Yu, Wilson; Smith, Autumn B.; Pilitsis, Julie; Shin, Damian S.


Book ID
122135537
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
843 KB
Volume
108
Category
Article
ISSN
0920-1211

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Extracellular field potential recordings were used to study the effects of the antiepileptic drugs (AEDs) carbamazepine (CBZ), phenytoin (PHT), phenobarbital (PhB) and valproic acid (VPA) on the epileptiform activity evoked by 4-aminopyridine (4-AP, 50 microM) in the CA3 subfield of rat hippocampal