Isotope-edited nuclear magnetic resonance: novel methodologies for investigating metabolism

✍ Scribed by Gard, Janice K; Hutton, William C; Baker, Jeanette A; Singh, RK; Feng, Paul CC

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 120 KB
• Volume: 55
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199902)55:2<215::aid-ps876>3.0.co;2-i

✦ Synopsis

While the use of NMR and stable isotopes in metabolism studies is hardly new, it is only recently that isotope-edited NMR spectroscopy has been applied in kinetic studies of glyphosate metabolism of soil microbes. NMR can detect multiple species simultaneously and non-destructively, yielding valuable information on structural identiücation of metabolites. spectroscopy Triple Resonance Isotope EDited (TRIED), [ 2H] NMR, and [ 2H-13C ] INEPT