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Isoquinolone Derivatives via a Furan Recyclization Reaction.

✍ Scribed by Artem S. Dmitriev; Vladimir T. Abaev; Wolfgang Bender; Alexander V. Butin

Book ID
102015668
Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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A general method for the synthesis of isocoumarine derivatives has been developed. Bis(5-R-2furyl)methylbenzoic acids (R = methyl, ethyl) underwent recyclization and subsequent cyclization into tetracyclic isochromene-1-one derivatives under treatment with hydrogen chloride in methanol. It has been