Isopropylidenemalononitrile in the Synthesis of 2-Amino-4,6,6-trimethylcyclohexa-2,4-diene-1,1,3-tricarbonitrile (IX), 6-Amino-2- (4-methoxybenzoylmethylsulfanyl) -4,4-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile (IV), and Fused 2-Aminopyrans (VI), (VIII) According to Michael.
β Scribed by V. D. Dyachenko; E. B. Rusanov
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 21 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The reaction of thiocarbohydrazide with carboxylic acids at the melting temperature allows an improved preparation of the Sβsubstituted 4βaminoβ3βmercaptoβ1,2,4βtriazole heterocycles. The crude 4βaminoβ5βmercaptoβ1,2,4βtriazoles react easily with carboxylic acids or carboxylic acid chlo
Synthesis of N-Methylmorpholinium 6-Amino-4-aryl-4-methyl-3,5dicyano-1,4-dihydropyridine-2-thiolates under Conditions of Michael Reaction. -Reaction of alkylidenemalononitriles (I) with cyanothioacetamide (II) affords the corresponding Michael adducts which cyclize immediately to the title 1,4-dihy