Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conrauiWarburg (Moraceae)

✍ Scribed by Rodrigue T. Kengap; Gilbert D. W. F. Kapche; Jean-Paul Dzoyem; Ingrid K. Simo; Pantaleon Ambassa; Louis P. Sandjo; Berhanu M. Abegaz; Bonaventure T. Ngadjui

• Book ID: 102258553
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: German
• Weight: 198 KB
• Volume: 94
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.201100173

✦ Synopsis

Abstract

A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with β‐amyrin acetate (3), betulinic acid (4), ursolic acid (5), 6__β__‐hydroxystigmasta‐4,22‐dien‐3‐one (6), 8‐prenylapigenin (7), β‐sitosterol glucoside (8), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone (9) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.