Isopenicillin N Synthase: An Enzyme at Work

✍ Scribed by Wolfdieter A. Schenk

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 180 KB
• Volume: 39
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20001002)39:19<3409::aid-anie3409>3.0.co;2-t

✦ Synopsis

The discovery of penicillin in 1929 [1] has revolutionized medicine. [2] Many of the potentially lethal bacterial infections lost their specter as life threatening diseasesÐ a situation which could change again soon. [3] The penicillins (Scheme 1) Scheme 1. Structures of a typical penicillin and a typical cephalosporin. Ac acetyl.