Isomerization of All-Trans-Retinoids to 11-Cis-Retinoids in vitro
β Scribed by Paul S. Bernstein, Wing C. Law and Robert R. Rando
- Book ID
- 123634211
- Publisher
- National Academy of Sciences
- Year
- 1987
- Tongue
- English
- Weight
- 892 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/29544
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π SIMILAR VOLUMES
The C7-C12 triene fragment of 9-cis-retinoids 8 was stereoselectively generated by treatment of propargylic alcohol 3 with phenylsulfenyl chloride/triethylamine at -78 Β°C, followed by stereospecific reduction of the resulting vinylsulfoxide (t-BuLi, MeLi, MeOH, -78 Β°C). Thus, 9-cis-retinoic acid 2,
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