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Isomerization of all - trans -9- and 13-Desmethylretinol by Retinal Pigment Epithelial Cells †

✍ Scribed by Stecher, Hartmut; Prezhdo, Oleg; Das, Joydip; Crouch, Rosalie K.; Palczewski, Krzysztof

Book ID
126876030
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
134 KB
Volume
38
Category
Article
ISSN
0006-2960

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Retinal pigment epithelial cells, which form one aspect of the blood-retinal barrier, take up iron in association with transferrin by a typical receptor-mediated mechanism (Hunt et al., 1989. J. Cell Sci. 92:655-666). This iron is dissociated from transferrin in a low pH environment and uptake is se