Isomerism of Amides Coordinated to Platinum – X-ray Crystal Structure of O-Bonded Acetamide in a Platinum(II) Complex

✍ Scribed by Renzo Cini; Francesco P. Intini; Luciana Maresca; Concetta Pacifico; Giovanni Natile

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 429 KB
• Volume: 1998
• Category: Article
• ISSN: 1434-1948
• DOI: 10.1002/(sici)1099-0682(199809)1998:9<1305::aid-ejic1305>3.0.co;2-9

✦ Synopsis

O-bonded amide complexes of platinum(II), which are stable species due to the higher affinity of platinum for nitrogen donors. In contrast O-bonded amides owe their stability to in acetone solution and which undergo solvolysis in neat water with a rate constant as slow as 8.7•10 -5 s -1 , are their kinetic inertness, where a high pH is required for deprotonation of the NH 2 moiety, the leading step in the reported. The structure of a sample compound [Pt(Me 5 dien)-{O-MeC(O)NH 2 }](CF 3 SO 3 ) 2 has been solved by X-ray isomerization process. In the case of the 2-pyridone complex, the O-bonded form is unstable and isomerizes spontaneously diffraction allowing comparison with related N-bonded (amide)platinum complexes. Isomerization from O-amide to to the N-bonded form, due to the higher acidity of the protonated pyridine-like nitrogen atom. Two rotamers are N-amidate species takes place instantaneously under basic conditions. Protonation of the amidate species leads to the N-present in both the N-pyridone and N-pyridonate species. Hindered rotation stems from the steric rigidity of both bonded amide. N-bonded amides, like the N-bonded amidates, represent the thermodynamically preferred rotating moieties [(Me 5 dien)Pt and pyridone/pyridonate].