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Isomeric Phenylalanyl-tRNAs. Position of the Aminoacyl Moiety during Protein Biosynthesis

✍ Scribed by Sidney M. Hecht, John W. Kozarich and Francis J. Schmidt


Book ID
123652914
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
964 KB
Volume
71
Category
Article
ISSN
0027-8424

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Leucyl/phenylalanyl(L/F)-tRNA-protein tr
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## Abstract We report here a new strategy for derivatizing peptides and proteins at the N‐terminus. To achieve this, a nonnatural amino acid was charged onto a tRNA and then enzymatically transferred to a lysine (Lys) unit at the N‐terminus of a peptide or a protein by using L/F‐tRNA‐protein transf