Isomer-specific determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds in human fat and food
✍ Scribed by H. Beck; K. Eckart; W. Mathar; Ch.-S. Rühl; R. Wittkowski
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 269 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1076-5174
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## Abstract 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) is known to alter carbohydrate utilization and specific steps in lipid metabolism. TCDD interacts with estradiol in mobilizing specific fatty acids in chickens that may be a cause of cranial/beak malformations in this species. This study was de
## Abstract ## BACKGROUND 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) is teratogenic in mice, producing cleft palate (CP). TCDD exposure disrupts expression of epidermal growth factor (EGF) receptor, EGF, and transforming growth factor‐α (TGFα) in the palate and affects proliferation and differenti