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Isolierung von Bradykinin aus Rinderplasma nach Einwirkung von Schlangengift (Bothrops jararaca). Vorläufige Mitteilung

✍ Scribed by H. Zuber; R. Jaques

Publisher: John Wiley and Sons
Year: 1960
Tongue: German
Weight: 247 KB
Volume: 43
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19600430422

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✦ Synopsis

Abstract

Bradykinin, resulting from the action of snake venom (Bothrops jararaca) on bovine plasma, has been isolated in an essentially pure form. It contains the five amino acids arginine, phenylalanine, proline, glycine and serine in the ratio of 2:2:2:1:1, corresponding to the amino acid composition found for bradykinin stemming from the action of trypsin on corresponding plasma proteins. Degradation studies give the following partial sequence: H·Arg‐(Pro~2~ Gly, Ser, Phe)‐Phe‐Arg·OH.

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Isolierung von Substanz P aus Pferdedarm und ihre biologische und chemische Abgrenzung gegenüber Bradykinin. Vorläufige Mitteilung

✍ J. Franz; R. A. Boissonnas; E. Stürmer 📂 Article 📅 1961 🏛 John Wiley and Sons 🌐 German ⚖ 229 KB

Substance P has been isolated in an apparently pure state and shown to be biologically and chemically distinct from Bradykinin though the two substances have some properties in common.