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Isolation, Synthesis, and Characterization of Impurities and Degradants from the Clofarabine Process

โœ Scribed by Anderson, Bruce G.; Bauta, William E.; Cantrell, Jr., William R.; Engles, Tracy; Lovett, Dennis P.


Book ID
119960428
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
194 KB
Volume
12
Category
Article
ISSN
1083-6160

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## Abstract A reversedโ€phase highโ€performance liquid chromatographic method for simultaneous separation and determination of citalopram hydrobromide and its process impurities in bulk drugs and pharmaceutical formulations was developed. The separation was accomplished on an Inertsil ODS 3V (250ร—4.6