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Isolation, structural characterization, and antiviral activity of positional isomers of monopegylated interferon α-2a (PEGASYS)

✍ Scribed by Stefan Foser; Alfred Schacher; Karl A Weyer; Doris Brugger; Elke Dietel; Stefan Marti; Thomas Schreitmüller


Book ID
117702726
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
509 KB
Volume
30
Category
Article
ISSN
1046-5928

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ment of Kaposi's sarcoma, chronic hepatitis B, hairy-The success of recombinant interferon a in the clinic cell leukemia, etc. (2, 3). in part is limited by two properties of the protein: One approach to improve serum half-life, decrease short serum half-life and immunogenicity. To imthe frequency