Positional Isomers of Monopegylated Inte
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Seth P. Monkarsh; Yuemei Ma; Anthony Aglione; Pascal Bailon; Doreen Ciolek; Bara
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Article
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1997
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Elsevier Science
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English
⚖ 133 KB
ment of Kaposi's sarcoma, chronic hepatitis B, hairy-The success of recombinant interferon a in the clinic cell leukemia, etc. (2, 3). in part is limited by two properties of the protein: One approach to improve serum half-life, decrease short serum half-life and immunogenicity. To imthe frequency