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Isolation of α,α-difluoroketene silyl acetal and its application to asymmetric aldol reactions

✍ Scribed by Katsuhiko Iseki; Yoshichika Kuroki; Daisuke Asada; Yoshiro Kobayashi


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
136 KB
Volume
38
Category
Article
ISSN
0040-4039

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The catalytic asymmetric aldol reaction
✍ Emma R. Parmee; Yaping Hong; Orin Tempkin; Satoru Masamune 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 272 KB

The title reaction with unsubstifufed and monosubstituted silyf ketene acetals proceeds with high enantioseiectivify, and in the latter case good dinstereoselecfivity favoring the anfi-/Chydrory-amethyl esters in all reported cases.