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Isolation of transporter associated with antigen processing genes,TAP1andTAP2, from the horned sharkHeterodontus francisci

✍ Scribed by Y. Ohta; D. E. Haliniewski; John Hansen; M. F. Flajnik


Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
284 KB
Volume
49
Category
Article
ISSN
0093-7711

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Stable cell surface presentation of HLA class I molecules requires active transport of antigenic peptides across the endoplasmic reticulum by products of two genes, TAP1 and TAP2, which map in the major histocompatibility complex class II region. Alleles of each gene are derived from a combination o