Isolation of the (E)-Enols of β-Ketocarboxylic Acid Derivatives
✍ Scribed by Prof. Dr. Herbert Meier; Dipl.-Chem. Wolfgang Lauer; Dr. Friedrich Ulrich Scholter
- Book ID
- 101556934
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 222 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0044-8249
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## Abstract Deprotonation of (__Z__)‐ or (__E__)‐3‐hydroxy‐2,3‐dimesitylpropenoic acid methyl ester (1a) with tetrakis(dimethylamino)‐methane (3) led to stable salt (__E__)‐2a, which belongs to a very rare species of salts that consist of a heteroatom‐stabilized carbocation and a heteroatom‐stabili
Various N-protected amino acids bearing an enol ether side chain were synthesized by a new method allowing a great versatility in the introduction of both the N-protective groups and the enol ether moieties. This method deals with a Wittig-Homer condensation to afford the a$-dehydro homoserine ether