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Isolation of Polyphenols from Polygala gazensis and Liquid Chromatography–Mass Spectrometry of Related African Polygala Species

✍ Scribed by Chantal Bergeron; Andrew Marston; Jean-Luc Wolfender; Stephen Mavi; Colin Rogers; Kurt Hostettmann

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
159 KB
Volume
8
Category
Article
ISSN
0958-0344

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✦ Synopsis

The chromonocoumarins frutinones A and B and lignans eudesmin, magnolin, yangambin and kobusin were isolated from lipophilic extract of P. gazensis. This species and two other related Polygala species were subsequently analysed by thermospray liquid chromatography-mass spectrometry and high pressure liquid chromatography coupled with photodiode-array detection. Frutinone A was also found in the roots and aerial parts of P. teretifolia and P. fruticosa, while the presence of frutinone B was limited principally to the roots. Lignans were present in the aerial parts of P. teretifolia. Frutinone A showed antifungal activity against Cladosporium cucumerinum and Candida albicans while eudesmin and kobusin were antifungal against Cladosporium cucumerinum only.

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