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Isolation of peptide ligands that interact specifically with human glioma cells

✍ Scribed by Ivy A.W. Ho; Kam M. Hui; Paula Y.P. Lam

Book ID
116832118
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
485 KB
Volume
31
Category
Article
ISSN
0196-9781

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Selection and initial characterization o
Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells
✍ Anka N. Veleva; Stuart L. Cooper; Cam Patterson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 202 KB

## Abstract Using phage display technology, we have isolated 12‐mer peptide ligands that bind to human blood outgrowth endothelial cells (HBOEC). To avoid non‐specific binding we apply negative–positive selection approach by pre‐incubating the library with non‐HBOEC. The selected phage clones bind