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Isolation of multiple protein factors involved in ribosomal DNA transcription

โœ Scribed by Gisela Heilgenthal; Ingrid Grummt

Book ID
103147562
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
782 KB
Volume
587
Category
Article
ISSN
1873-3778

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Faithful and efficient transcription initiation at the mouse ribosomal gene promoter requires besides RNA polymerase I (pol I) four polypeptide trans-acting factors, termed TIF-IA, TIF-IB, TIF-IC, and mUBF. We have partially purified these proteins from cultured Ehrlich ascites cells and show that i